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Epigallocathechin-O-3-Gallate Inhibits Trypanothione Reductase of Leishmania infantum, Causing Alterations in Redox Balance and Leading to Parasite Death

Leishmania infantum is a protozoan parasite that causes a vector borne infectious disease in humans known as visceral leishmaniasis (VL). This pathology, also caused by L. donovani, presently impacts the health of 500,000 people worldwide, and is treated with outdated anti-parasitic drugs that suffe...

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書目詳細資料
發表在:Front Cell Infect Microbiol
Main Authors: Inacio, Job D. F., Fonseca, Myslene S., Limaverde-Sousa, Gabriel, Tomas, Ana M., Castro, Helena, Almeida-Amaral, Elmo E.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027256/
https://ncbi.nlm.nih.gov/pubmed/33842389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.640561
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