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Epigallocathechin-O-3-Gallate Inhibits Trypanothione Reductase of Leishmania infantum, Causing Alterations in Redox Balance and Leading to Parasite Death

Leishmania infantum is a protozoan parasite that causes a vector borne infectious disease in humans known as visceral leishmaniasis (VL). This pathology, also caused by L. donovani, presently impacts the health of 500,000 people worldwide, and is treated with outdated anti-parasitic drugs that suffe...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Inacio, Job D. F., Fonseca, Myslene S., Limaverde-Sousa, Gabriel, Tomas, Ana M., Castro, Helena, Almeida-Amaral, Elmo E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027256/
https://ncbi.nlm.nih.gov/pubmed/33842389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.640561
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