Epigallocathechin-O-3-Gallate Inhibits Trypanothione Reductase of Leishmania infantum, Causing Alterations in Redox Balance and Leading to Parasite Death

Leishmania infantum is a protozoan parasite that causes a vector borne infectious disease in humans known as visceral leishmaniasis (VL). This pathology, also caused by L. donovani, presently impacts the health of 500,000 people worldwide, and is treated with outdated anti-parasitic drugs that suffe...

Full description

Saved in:
Bibliographic Details
Published in:Front Cell Infect Microbiol
Main Authors: Inacio, Job D. F., Fonseca, Myslene S., Limaverde-Sousa, Gabriel, Tomas, Ana M., Castro, Helena, Almeida-Amaral, Elmo E.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Cellular and Infection Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027256/
https://ncbi.nlm.nih.gov/pubmed/33842389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.640561
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items