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Three-Component 1,2-Carboamidation of Bridged Bicyclic Alkenes via Rh(III)-Catalyzed Addition of C–H Bonds and Amidating Reagents

A three-component method is described for the preparation of syn-1,2-disubstituted bridged bicyclic compounds. The reaction was demonstrated for readily available aromatic and heteroaromatic C–H bond substrates with tertiary and secondary amide, lactam, pyrazole and triazole directing groups, and a...

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Enregistré dans:
Détails bibliographiques
Publié dans:Org Lett
Auteurs principaux: Brandes, Daniel S., Sirvent, Ana, Mercado, Brandon Q., Ellman, Jonathan A.
Format: Artigo
Langue:Inglês
Publié: 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026749/
https://ncbi.nlm.nih.gov/pubmed/33739839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.1c00851
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