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Rh(III)-Catalyzed Imidoyl C–H Carbamylation and Cyclization to Bicyclic [1,3,5]Triazinones

A Rh(III)-catalyzed synthesis of bicyclic [1,3,5]triazinones from a diverse array of imines coupled with ethyl (pivaloyloxy)carbamate is reported. The preparation of [5,6]- and [6,6]-bicyclic heterocycles substituted with aryl, alkyl and alkoxy groups demonstrated a broad reaction scope. The efficie...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Confair, Danielle N., Greenwood, Nathaniel S., Mercado, Brandon Q., Ellman, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7702018/
https://ncbi.nlm.nih.gov/pubmed/33172274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c03393
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