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Cobalt(III)-Catalyzed Diastereoselective Three-Component C–H Bond Addition to Butadiene and Activated Ketones

A highly diastereoselective three-component C–H bond addition across butadiene and activated ketones is described. This transformation provides homoallylic tertiary alcohols through the formation of two C–C σ bonds and with complete selectivity for an E-alkene isomer. The reaction exhibits good scop...

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Bibliographic Details
Published in:Synthesis (Stuttg)
Main Authors: Shen, Zican, Li, Chen, Mercado, Brandon Q., Ellman, Jonathan A.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7462114/
https://ncbi.nlm.nih.gov/pubmed/32884161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0039-1690741
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