A Universal Allosteric Mechanism for G Protein Activation.

G proteins play a central role in signal transduction and pharmacology. Signaling is initiated by cell-surface receptors, which promote GTP binding and the dissociation of Gα from the Gβγ subunits. Structural studies have revealed the molecular basis for subunit association with receptors, RGS prote...

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發表在:Mol Cell
Main Authors: Knight, Kevin M., Ghosh, Soumadwip, Campbell, Sharon L., Lefevre, Tyler J., Olsen, Reid H. J., Smrcka, Alan V., Valentin, Natalie H., Yin, Guowei, Vaidehi, Nagarajan, Dohlman, Henrik G.
格式: Artigo
語言:Inglês
出版: 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026646/
https://ncbi.nlm.nih.gov/pubmed/33636126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2021.02.002
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