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Simplitigs as an efficient and scalable representation of de Bruijn graphs

de Bruijn graphs play an essential role in bioinformatics, yet they lack a universal scalable representation. Here, we introduce simplitigs as a compact, efficient, and scalable representation, and ProphAsm, a fast algorithm for their computation. For the example of assemblies of model organisms and...

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Bibliografische gegevens
Gepubliceerd in:Genome Biol
Hoofdauteurs: Břinda, Karel, Baym, Michael, Kucherov, Gregory
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025321/
https://ncbi.nlm.nih.gov/pubmed/33823902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-021-02297-z
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