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Space-efficient and exact de Bruijn graph representation based on a Bloom filter

BACKGROUND: The de Bruijn graph data structure is widely used in next-generation sequencing (NGS). Many programs, e.g. de novo assemblers, rely on in-memory representation of this graph. However, current techniques for representing the de Bruijn graph of a human genome require a large amount of memo...

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Detalhes bibliográficos
Main Authors: Chikhi, Rayan, Rizk, Guillaume
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848682/
https://ncbi.nlm.nih.gov/pubmed/24040893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7188-8-22
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