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Basic mechanism of the autonomous ClpG disaggregase

Bacterial survival during lethal heat stress relies on the cellular ability to reactivate aggregated proteins. This activity is typically executed by the canonical 70-kDa heat shock protein (Hsp70)–ClpB bichaperone disaggregase, which is most widespread in bacteria. The ClpB disaggregase is a member...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Katikaridis, Panagiotis, Römling, Ute, Mogk, Axel
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024975/
https://ncbi.nlm.nih.gov/pubmed/33639171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100460
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