Stand-alone ClpG disaggregase confers superior heat tolerance to bacteria

AAA+ disaggregases solubilize aggregated proteins and confer heat tolerance to cells. Their disaggregation activities crucially depend on partner proteins, which target the AAA+ disaggregases to protein aggregates while concurrently stimulating their ATPase activities. Here, we report on two potent...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Lee, Changhan, Franke, Kamila B., Kamal, Shady Mansour, Kim, Hyunhee, Lünsdorf, Heinrich, Jäger, Jasmin, Nimtz, Manfred, Trček, Janja, Jänsch, Lothar, Bukau, Bernd, Mogk, Axel, Römling, Ute
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
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PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777039/
https://ncbi.nlm.nih.gov/pubmed/29263094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712051115
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