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Basic mechanism of the autonomous ClpG disaggregase

Bacterial survival during lethal heat stress relies on the cellular ability to reactivate aggregated proteins. This activity is typically executed by the canonical 70-kDa heat shock protein (Hsp70)–ClpB bichaperone disaggregase, which is most widespread in bacteria. The ClpB disaggregase is a member...

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Publicado en:J Biol Chem
Main Authors: Katikaridis, Panagiotis, Römling, Ute, Mogk, Axel
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024975/
https://ncbi.nlm.nih.gov/pubmed/33639171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100460
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