Allosterism vs. Orthosterism: Recent Findings and Future Perspectives on A(2B) AR Physio-Pathological Implications

The development of GPCR (G-coupled protein receptor) allosteric modulators has attracted increasing interest in the last decades. The use of allosteric modulators in therapy offers several advantages with respect to orthosteric ones, as they can fine-tune the tissue responses to the endogenous agoni...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Autores principales: Barresi, Elisabetta, Martini, Claudia, Da Settimo, Federico, Greco, Giovanni, Taliani, Sabrina, Giacomelli, Chiara, Trincavelli, Maria Letizia
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024542/
https://ncbi.nlm.nih.gov/pubmed/33841166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.652121
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