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Allosterism vs. Orthosterism: Recent Findings and Future Perspectives on A(2B) AR Physio-Pathological Implications

The development of GPCR (G-coupled protein receptor) allosteric modulators has attracted increasing interest in the last decades. The use of allosteric modulators in therapy offers several advantages with respect to orthosteric ones, as they can fine-tune the tissue responses to the endogenous agoni...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Barresi, Elisabetta, Martini, Claudia, Da Settimo, Federico, Greco, Giovanni, Taliani, Sabrina, Giacomelli, Chiara, Trincavelli, Maria Letizia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024542/
https://ncbi.nlm.nih.gov/pubmed/33841166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.652121
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