Novel positive allosteric modulators of A(2B) adenosine receptor acting as bone mineralisation promoters

Small-molecules acting as positive allosteric modulators (PAMs) of the A(2B) adenosine receptor (A(2B) AR) could potentially represent a novel therapeutic strategy for pathological conditions characterised by altered bone homeostasis, including osteoporosis. We investigated a library of compounds (4...

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Bibliographic Details
Published in:J Enzyme Inhib Med Chem
Main Authors: Barresi, Elisabetta, Giacomelli, Chiara, Marchetti, Laura, Baglini, Emma, Salerno, Silvia, Greco, Giovanni, Da Settimo, Federico, Martini, Claudia, Trincavelli, Maria Letizia, Taliani, Sabrina
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2020
Subjects:
Brief Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751416/
https://ncbi.nlm.nih.gov/pubmed/33334192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1862103
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