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The Alpha Keto Amide Moiety as a Privileged Motif in Medicinal Chemistry: Current Insights and Emerging Opportunities

[Image: see text] Over the years, researchers in drug discovery have taken advantage of the use of privileged structures to design innovative hit/lead molecules. The α-ketoamide motif is found in many natural products, and it has been widely exploited by medicinal chemists to develop compounds tailo...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Robello, Marco, Barresi, Elisabetta, Baglini, Emma, Salerno, Silvia, Taliani, Sabrina, Settimo, Federico Da
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8154582/
https://ncbi.nlm.nih.gov/pubmed/33764065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c01808
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