TSPO ligand residence time: a new parameter to predict compound neurosteroidogenic efficacy

The pharmacological activation of the cholesterol-binding Translocator Protein (TSPO) leads to an increase of endogenous steroids and neurosteroids determining benefic pleiotropic effects in several pathological conditions, including anxiety disorders. The relatively poor relationship between TSPO l...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Costa, Barbara, Da Pozzo, Eleonora, Giacomelli, Chiara, Barresi, Elisabetta, Taliani, Sabrina, Da Settimo, Federico, Martini, Claudia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707509/
https://ncbi.nlm.nih.gov/pubmed/26750656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18164
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