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Vangl2 promotes the formation of long cytonemes to enable distant Wnt/β-catenin signaling

Wnt signaling regulates cell proliferation and cell differentiation as well as migration and polarity during development. However, it is still unclear how the Wnt ligand distribution is precisely controlled to fulfil these functions. Here, we show that the planar cell polarity protein Vangl2 regulat...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Brunt, Lucy, Greicius, Gediminas, Rogers, Sally, Evans, Benjamin D., Virshup, David M., Wedgwood, Kyle C. A., Scholpp, Steffen
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024337/
https://ncbi.nlm.nih.gov/pubmed/33824332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22393-9
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