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Vangl2 promotes the formation of long cytonemes to enable distant Wnt/β-catenin signaling

Wnt signaling regulates cell proliferation and cell differentiation as well as migration and polarity during development. However, it is still unclear how the Wnt ligand distribution is precisely controlled to fulfil these functions. Here, we show that the planar cell polarity protein Vangl2 regulat...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Brunt, Lucy, Greicius, Gediminas, Rogers, Sally, Evans, Benjamin D., Virshup, David M., Wedgwood, Kyle C. A., Scholpp, Steffen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024337/
https://ncbi.nlm.nih.gov/pubmed/33824332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22393-9
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