A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis

A novel coumarin-based molecule, designed as a fluorescent surrogate of a thiacetazone-derived antitubercular agent, was quickly and easily synthesized from readily available starting materials. This small molecule, coined as Coum-TAC, exhibited a combination of appropriate physicochemical and biolo...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:ACS Infect Dis
Hlavní autoři: Farjallah, Asma, Chiarelli, Laurent R., Forbak, Martin, Degiacomi, Giulia, Danel, Mathieu, Goncalves, Fernanda, Carayon, Chantal, Seguin, Cendrine, Fumagalli, Marco, Záhorszká, Monika, Vega, Elodie, Abid, Souhir, Grzegorzewicz, Anna, Jackson, Mary, Peixoto, Antonio, Korduláková, Jana, Pasca, Maria Rosalia, Lherbet, Christian, Chassaing, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8022203/
https://ncbi.nlm.nih.gov/pubmed/33617235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00325
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky