Catastrophic ATP loss underlies a metabolic combination therapy tailored for MYCN-amplified neuroblastoma

MYCN-amplified neuroblastoma is a lethal subset of pediatric cancer. MYCN drives numerous effects in the cell, including metabolic changes that are critical for oncogenesis. The understanding that both compensatory pathways and intrinsic redundancy in cell systems exists implies that the use of comb...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Dalton, Krista M., Lochmann, Timothy L., Floros, Konstantinos V., Calbert, Marissa L., Kurupi, Richard, Stein, Giovanna T., McClanaghan, Joseph, Murchie, Ellen, Egan, Regina K., Greninger, Patricia, Dozmorov, Mikhail, Ramamoorthy, Sivapriya, Puchalapalli, Madhavi, Hu, Bin, Shock, Lisa, Koblinski, Jennifer, Glod, John, Boikos, Sosipatros A., Benes, Cyril H., Faber, Anthony C.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2021
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020796/
https://ncbi.nlm.nih.gov/pubmed/33762304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2009620118
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars