Novel reporter mouse models useful for evaluating in vivo gene editing and for optimization of methods of delivering genome editing tools

The clustered regularly interspersed palindromic repeats (CRISPR) system is a powerful genome-editing tool to modify genomes, virtually in any species. The CRISPR tool has now been utilized in many areas of medical research, including gene therapy. Although several proof-of-concept studies show the...

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Dettagli Bibliografici
Pubblicato in:Mol Ther Nucleic Acids
Autori principali: Miura, Hiromi, Imafuku, Jurai, Kurosaki, Aki, Sato, Masahiro, Ma, Yongjie, Zhang, Guisheng, Mizutani, Akiko, Kamimura, Kenya, Gurumurthy, Channabasavaiah B., Liu, Dexi, Ohtsuka, Masato
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2021
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020343/
https://ncbi.nlm.nih.gov/pubmed/33850636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.03.003
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