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An ATM-CHK2-INCENP pathway prevents chromatin breakage by regulating the abscission checkpoint

In response to chromatin bridges, the chromosomal passenger complex (CPC) delays completion of cytokinesis (abscission) to prevent chromosome breakage. Here, we discuss recent findings from our lab showing that an ATM-CHK2-INCENP pathway imposes the abscission checkpoint in human cells by regulating...

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Publicado en:Mol Cell Oncol
Main Authors: Petsalaki, Eleni, Zachos, George
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018396/
https://ncbi.nlm.nih.gov/pubmed/33860082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2021.1877999
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