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An ATM-CHK2-INCENP pathway prevents chromatin breakage by regulating the abscission checkpoint

In response to chromatin bridges, the chromosomal passenger complex (CPC) delays completion of cytokinesis (abscission) to prevent chromosome breakage. Here, we discuss recent findings from our lab showing that an ATM-CHK2-INCENP pathway imposes the abscission checkpoint in human cells by regulating...

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Bibliografische gegevens
Gepubliceerd in:Mol Cell Oncol
Hoofdauteurs: Petsalaki, Eleni, Zachos, George
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018396/
https://ncbi.nlm.nih.gov/pubmed/33860082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2021.1877999
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