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The ASXL1-G643Wvariant accelerates the development of CEBPA mutant acute myeloid leukemia
ASXL1 is one of the most commonly mutated genes in myeloid malignancies, including myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). In order to further our understanding of the role of ASXL1 lesions in malignant hematopoiesis, we generated a novel knockin mouse model carrying the mos...
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| Udgivet i: | Haematologica |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Fondazione Ferrata Storti
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8017816/ https://ncbi.nlm.nih.gov/pubmed/32381577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.235150 |
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