The splicing factor RBM25 controls MYC activity in acute myeloid leukemia

Cancer sequencing studies have implicated regulators of pre-mRNA splicing as important disease determinants in acute myeloid leukemia (AML), but the underlying mechanisms have remained elusive. We hypothesized that “non-mutated” splicing regulators may also play a role in AML biology and therefore c...

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Udgivet i:Nat Commun
Main Authors: Ge, Ying, Schuster, Mikkel Bruhn, Pundhir, Sachin, Rapin, Nicolas, Bagger, Frederik Otzen, Sidiropoulos, Nikos, Hashem, Nadia, Porse, Bo Torben
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329799/
https://ncbi.nlm.nih.gov/pubmed/30635567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08076-y
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