PAK4 suppresses motor neuron degeneration in hSOD1(G93A)‐linked amyotrophic lateral sclerosis cell and rat models

OBJECTIVES: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motor neurons (MN). CREB pathway‐mediated inhibition of apoptosis contributes to neuron protection, and PAK4 activates CREB signalling in diverse cell types. This study aimed...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Cong, Chaohua, Liang, Weiwei, Zhang, Chunting, Wang, Ying, Yang, Yueqing, Wang, Xudong, Wang, Shuyu, Huo, Di, Wang, Hongyong, Wang, Di, Feng, Honglin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016643/
https://ncbi.nlm.nih.gov/pubmed/33615605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.13003
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados