Compensatory Motor Neuron Response to Chromatolysis in the Murine hSOD1(G93A) Model of Amyotrophic Lateral Sclerosis

We investigated neuronal self-defense mechanisms in a murine model of amyotrophic lateral sclerosis (ALS), the transgenic hSOD1(G93A), during both the asymptomatic and symptomatic stages. This is an experimental model of endoplasmic reticulum (ER) stress with severe chromatolysis. As a compensatory...

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Main Authors: Riancho, Javier, Ruiz-Soto, Maria, Villagrá, Nuria T., Berciano, Jose, Berciano, Maria T., Lafarga, Miguel
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2014
主題:
Neuroscience
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206191/
https://ncbi.nlm.nih.gov/pubmed/25374511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00346
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