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Absence of toll-like receptor 4 (TLR4) extends survival in the hSOD1(G93A) mouse model of amyotrophic lateral sclerosis
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a devastating late onset neurodegenerative disorder that is characterised by the progressive loss of upper and lower motor neurons. The mechanisms underlying ALS pathogenesis are unclear; however, there is emerging evidence the innate immune system,...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Neuroinflammation |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4431460/ https://ncbi.nlm.nih.gov/pubmed/25962427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0310-z |
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