Complement C5a-C5aR1 signalling drives skeletal muscle macrophage recruitment in the hSOD1(G93A) mouse model of amyotrophic lateral sclerosis

BACKGROUND: The terminal pathway of the innate immune complement system is implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS). Terminal complement activation leads to generation of C5a, which through its receptor, C5aR1, drives immune cell recruitment and activation. Importantly,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Skelet Muscle
मुख्य लेखकों: Wang, Haitao A., Lee, John D., Lee, Kah Meng, Woodruff, Trent M., Noakes, Peter G.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2017
विषय:
Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455206/
https://ncbi.nlm.nih.gov/pubmed/28571586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-017-0128-8
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन