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Effect of Epidermal Growth Factor Treatment and Polychlorinated Biphenyl Exposure in a Dietary-Exposure Mouse Model of Steatohepatitis

BACKGROUND: Polychlorinated biphenyls (PCBs) are signaling disrupting chemicals that exacerbate nonalcoholic steatohepatitis (NASH) in mice. They are epidermal growth factor receptor (EGFR) inhibitors that enhance hepatic inflammation and fibrosis in mice. OBJECTIVES: This study tested the hypothesi...

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Detalhes bibliográficos
Publicado no:Environ Health Perspect
Main Authors: Hardesty, Josiah E., Wahlang, Banrida, Prough, Russell A., Head, Kim Z., Wilkey, Daniel, Merchant, Michael, Shi, Hongxue, Jin, Jian, Cave, Matthew C.
Formato: Artigo
Idioma:Inglês
Publicado em: Environmental Health Perspectives 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011667/
https://ncbi.nlm.nih.gov/pubmed/33788613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP8222
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