Hepatic signalling disruption by pollutant Polychlorinated biphenyls in steatohepatitis

BACKGROUND: Polychlorinated biphenyl-mediated steatohepatitis has been shown to be due in part to inhibition of epidermal growth factor receptor (EGFR) signalling. EGFR signalling regulates many facets of hepatocyte function, but it is unclear which other kinases and pathways are involved in the dev...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Signal
Hauptverfasser: Hardesty, Josiah E., Wahlang, Banrida, Falkner, K. Cameron, Shi, Hongxue, Jin, Jian, Wilkey, Daniel, Merchant, Michael, Watson, Corey, Prough, Russell A., Cave, Matthew C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289731/
https://ncbi.nlm.nih.gov/pubmed/30300668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2018.10.004
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