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Hepatic signalling disruption by pollutant Polychlorinated biphenyls in steatohepatitis

BACKGROUND: Polychlorinated biphenyl-mediated steatohepatitis has been shown to be due in part to inhibition of epidermal growth factor receptor (EGFR) signalling. EGFR signalling regulates many facets of hepatocyte function, but it is unclear which other kinases and pathways are involved in the dev...

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Detalhes bibliográficos
Publicado no:Cell Signal
Main Authors: Hardesty, Josiah E., Wahlang, Banrida, Falkner, K. Cameron, Shi, Hongxue, Jin, Jian, Wilkey, Daniel, Merchant, Michael, Watson, Corey, Prough, Russell A., Cave, Matthew C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289731/
https://ncbi.nlm.nih.gov/pubmed/30300668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2018.10.004
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