Hepatic signalling disruption by pollutant Polychlorinated biphenyls in steatohepatitis

BACKGROUND: Polychlorinated biphenyl-mediated steatohepatitis has been shown to be due in part to inhibition of epidermal growth factor receptor (EGFR) signalling. EGFR signalling regulates many facets of hepatocyte function, but it is unclear which other kinases and pathways are involved in the dev...

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Опубликовано в: :Cell Signal
Главные авторы: Hardesty, Josiah E., Wahlang, Banrida, Falkner, K. Cameron, Shi, Hongxue, Jin, Jian, Wilkey, Daniel, Merchant, Michael, Watson, Corey, Prough, Russell A., Cave, Matthew C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289731/
https://ncbi.nlm.nih.gov/pubmed/30300668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2018.10.004
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