Proteomic analysis reveals novel mechanisms by which polychlorinated biphenyls compromise the liver promoting diet-induced steatohepatitis

BACKGROUND: Environmental pollution contributes to fatty liver disease pathogenesis. Polychlorinated biphenyl (PCB) exposures have been associated with liver enzyme elevation and suspected steatohepatitis in cohort studies. Male mice treated with the commercial PCB mixture, Aroclor 1260 (20 mg/kg),...

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Udgivet i:J Proteome Res
Main Authors: Hardesty, Josiah E., Wahlang, Banrida, Falkner, K. Cameron, Shi, Hongxue, Jin, Jian, Zhou, Yun, Wilkey, Daniel W., Merchant, Michael L., Watson, Corey T., Feng, Wenke, Morris, Andrew J., Hennig, Bernhard, Prough, Russell A., Cave, Matthew C.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059562/
https://ncbi.nlm.nih.gov/pubmed/30807179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.8b00886
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