Polychlorinated Biphenyls Disrupt Hepatic Epidermal Growth Factor Receptor Signaling

1. Polychlorinated biphenyls (PCBs) are persistent environmental pollutants that disrupt hepatic xenobiotic and intermediary metabolism, leading to metabolic syndrome and nonalcoholic steatohepatitis (NASH). 2. Since phenobarbital indirectly activates Constitutive Androstane Receptor (CAR) by antago...

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Detalhes bibliográficos
Publicado no:Xenobiotica
Main Authors: Hardesty, Josiah E., Wahlang, Banrida, Falkner, K. Cameron, Clair, Heather B., Clark, Barbara J., Ceresa, Brian P., Prough, Russell A., Cave, Matthew C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512701/
https://ncbi.nlm.nih.gov/pubmed/27458090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00498254.2016.1217572
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