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Polychlorinated Biphenyls Disrupt Hepatic Epidermal Growth Factor Receptor Signaling

1. Polychlorinated biphenyls (PCBs) are persistent environmental pollutants that disrupt hepatic xenobiotic and intermediary metabolism, leading to metabolic syndrome and nonalcoholic steatohepatitis (NASH). 2. Since phenobarbital indirectly activates Constitutive Androstane Receptor (CAR) by antago...

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Bibliografiska uppgifter
I publikationen:Xenobiotica
Huvudupphovsmän: Hardesty, Josiah E., Wahlang, Banrida, Falkner, K. Cameron, Clair, Heather B., Clark, Barbara J., Ceresa, Brian P., Prough, Russell A., Cave, Matthew C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512701/
https://ncbi.nlm.nih.gov/pubmed/27458090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00498254.2016.1217572
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