Concentration Dependence of Human and Mouse Aryl Hydrocarbon Receptor Responsiveness to Polychlorinated Biphenyl Exposures: Implications for Aroclor Mixtures

1. Aryl hydrocarbon receptor (AhR) ligands, including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs), are endocrine disrupting chemicals associated with nonalcoholic fatty liver disease. This study documents the species-specific differences between mouse (high affini...

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Publicado en:Xenobiotica
Autores principales: Shi, Hongxue, Hardesty, Josiah E., Jan, Jian, Head, Kimberly Z., Falkner, K. Cameron, Cave, Matthew C., Prough, Russell A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764862/
https://ncbi.nlm.nih.gov/pubmed/30991879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00498254.2019.1566582
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