A Therapeutic Strategy to Combat HIV-1 Latently Infected Cells With a Combination of Latency-Reversing Agents Containing DAG-Lactone PKC Activators

Advances in antiviral therapy have dramatically improved the therapeutic effects on HIV type 1 (HIV-1) infection. However, even with potent combined antiretroviral therapy, HIV-1 latently infected cells cannot be fully eradicated. Latency-reversing agents (LRAs) are considered a potential tool for e...

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Udgivet i:Front Microbiol
Main Authors: Matsuda, Kouki, Kobayakawa, Takuya, Kariya, Ryusho, Tsuchiya, Kiyoto, Ryu, Shoraku, Tsuji, Kohei, Ishii, Takahiro, Gatanaga, Hiroyuki, Yoshimura, Kazuhisa, Okada, Seiji, Hamada, Akinobu, Mitsuya, Hiroaki, Tamamura, Hirokazu, Maeda, Kenji
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010149/
https://ncbi.nlm.nih.gov/pubmed/33815322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2021.636276
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