Optic nerve regeneration screen identifies multiple genes restricting adult neural repair

Adult mammalian central nervous system (CNS) trauma interrupts neural networks and, because axonal regeneration is minimal, neurological deficits persist. Repair via axonal growth is limited by extracellular inhibitors and cell-autonomous factors. Based on results from a screen in vitro, we evaluate...

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Publicat a:Cell Rep
Autors principals: Lindborg, Jane A., Tran, Nicholas M., Chenette, Devon M., DeLuca, Kristin, Foli, Yram, Kannan, Ramakrishnan, Sekine, Yuichi, Wang, Xingxing, Wollan, Marius, Kim, In-Jung, Sanes, Joshua R., Strittmatter, Stephen M.
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009559/
https://ncbi.nlm.nih.gov/pubmed/33657370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108777
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