Inhibition of Poly-ADP-Ribosylation Fails to Increase Axonal Regeneration or Improve Functional Recovery after Adult Mammalian CNS Injury

After traumatic damage of the brain or spinal cord, many surviving neurons are disconnected, and recovery of function is limited by poor axon regeneration. Recent data have suggested that poly ADP-ribosylation plays a role in limiting axonal regrowth such that inhibition of poly (ADP-ribose) polymer...

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Xehetasun bibliografikoak
Argitaratua izan da:eNeuro
Egile Nagusiak: Wang, Xingxing, Sekine, Yuichi, Byrne, Alexandra B., Cafferty, William B.J., Hammarlund, Marc, Strittmatter, Stephen M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2016
Gaiak:
Negative Results
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5187389/
https://ncbi.nlm.nih.gov/pubmed/28032120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0270-16.2016
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