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Myelin-derived ephrinB3 restricts axonal regeneration and recovery after adult CNS injury

Recovery of neurological function after traumatic injury of the adult mammalian central nervous system is limited by lack of axonal growth. Myelin-derived inhibitors contribute to axonal growth restriction, with ephrinB3 being a developmentally important axonal guidance cue whose expression in matur...

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Autori principali: Duffy, Philip, Wang, Xingxing, Siegel, Chad S., Tu, Nathan, Henkemeyer, Mark, Cafferty, William B. J., Strittmatter, Stephen M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323955/
https://ncbi.nlm.nih.gov/pubmed/22411787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113953109
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