Optic nerve regeneration screen identifies multiple genes restricting adult neural repair

Adult mammalian central nervous system (CNS) trauma interrupts neural networks and, because axonal regeneration is minimal, neurological deficits persist. Repair via axonal growth is limited by extracellular inhibitors and cell-autonomous factors. Based on results from a screen in vitro, we evaluate...

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Pubblicato in:Cell Rep
Autori principali: Lindborg, Jane A., Tran, Nicholas M., Chenette, Devon M., DeLuca, Kristin, Foli, Yram, Kannan, Ramakrishnan, Sekine, Yuichi, Wang, Xingxing, Wollan, Marius, Kim, In-Jung, Sanes, Joshua R., Strittmatter, Stephen M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009559/
https://ncbi.nlm.nih.gov/pubmed/33657370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108777
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