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Functional Genome-wide Screen Identifies Pathways Restricting Central Nervous System Axonal Regeneration
Axonal regrowth is crucial for recovery from CNS injury but is severely restricted in adult mammals. We used a genome-wide loss-of-function screen for factors limiting axonal regeneration from cerebral cortical neurons in vitro. Knockdown of 16,007 individual genes identified 580 significant phenoty...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5937716/ https://ncbi.nlm.nih.gov/pubmed/29642001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.03.058 |
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