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Boosting GWAS using biological networks: A study on susceptibility to familial breast cancer
Genome-wide association studies (GWAS) explore the genetic causes of complex diseases. However, classical approaches ignore the biological context of the genetic variants and genes under study. To address this shortcoming, one can use biological networks, which model functional relationships, to sea...
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| Pubblicato in: | PLoS Comput Biol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8009366/ https://ncbi.nlm.nih.gov/pubmed/33735170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008819 |
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