Boosting GWAS using biological networks: A study on susceptibility to familial breast cancer

Genome-wide association studies (GWAS) explore the genetic causes of complex diseases. However, classical approaches ignore the biological context of the genetic variants and genes under study. To address this shortcoming, one can use biological networks, which model functional relationships, to sea...

Full description

Saved in:
Bibliographic Details
Published in:PLoS Comput Biol
Main Authors: Climente-González, Héctor, Lonjou, Christine, Lesueur, Fabienne, Stoppa-Lyonnet, Dominique, Andrieu, Nadine, Azencott, Chloé-Agathe
Format: Artigo
Language:Inglês
Published: Public Library of Science 2021
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009366/
https://ncbi.nlm.nih.gov/pubmed/33735170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008819
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items