Chemotherapy regimens induce inhibitory immune checkpoint protein expression on stem-like and senescent-like oesophageal adenocarcinoma cells

Use of immune checkpoint inhibitors (ICIs) with chemotherapy to enhance responses in oesophageal adenocarcinoma (OAC) is an attractive approach. We identified subpopulations of OAC cells expressing inhibitory immune checkpoint (IC) ligands (PD-L1, PD-L2 and CD160) and receptors (PD-1, TIGIT, TIM-3,...

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Vydáno v:Transl Oncol
Hlavní autoři: Davern, Maria, Donlon, Noel E., Sheppard, Andrew, Connell, Fiona O’, Hayes, Conall, Bhardwaj, Anshul, Foley, Emma, Toole, Dermot O’, Lynam-Lennon, Niamh, Ravi, Narayanasamy, Reynolds, John V., Maher, Stephen G., Lysaght, Joanne
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2021
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8008239/
https://ncbi.nlm.nih.gov/pubmed/33765543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2021.101062
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