Altered Mitochondrial Function and Energy Metabolism Is Associated with a Radioresistant Phenotype in Oesophageal Adenocarcinoma

Neoadjuvant chemoradiation therapy (CRT) is increasingly the standard of care for locally advanced oesophageal cancer. A complete pathological response to CRT is associated with a favourable outcome. Radiation therapy is important for local tumour control, however, radioresistance remains a substant...

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Main Authors: Lynam-Lennon, Niamh, Maher, Stephen G., Maguire, Aoife, Phelan, James, Muldoon, Cian, Reynolds, John V., O’Sullivan, Jacintha
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072695/
https://ncbi.nlm.nih.gov/pubmed/24968221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100738
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