Real-time metabolic profiling of oesophageal tumours reveals an altered metabolic phenotype to different oxygen tensions and to treatment with Pyrazinib

Oesophageal cancer is the 6th most common cause of cancer related death worldwide. The current standard of care for oesophageal adenocarcinoma (OAC) focuses on neoadjuvant therapy with chemoradiation or chemotherapy, however the 5-year survival rates remain at < 20%. To improve treatment outcomes...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Rep
Κύριοι συγγραφείς: Buckley, Amy M., Dunne, Margaret R., Morrissey, Maria E., Kennedy, Susan A., Nolan, Aoife, Davern, Maria, Foley, Emma K., Clarke, Niamh, Lysaght, Joanne, Ravi, Narayanasamy, O’Toole, Dermot, MacCarthy, Finbar, Reynolds, John V., Kennedy, Breandán N., O’Sullivan, Jacintha
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2020
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7374542/
https://ncbi.nlm.nih.gov/pubmed/32694701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68777-7
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