Real-time metabolic profiling of oesophageal tumours reveals an altered metabolic phenotype to different oxygen tensions and to treatment with Pyrazinib

Oesophageal cancer is the 6th most common cause of cancer related death worldwide. The current standard of care for oesophageal adenocarcinoma (OAC) focuses on neoadjuvant therapy with chemoradiation or chemotherapy, however the 5-year survival rates remain at < 20%. To improve treatment outcomes...

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Publicado no:Sci Rep
Main Authors: Buckley, Amy M., Dunne, Margaret R., Morrissey, Maria E., Kennedy, Susan A., Nolan, Aoife, Davern, Maria, Foley, Emma K., Clarke, Niamh, Lysaght, Joanne, Ravi, Narayanasamy, O’Toole, Dermot, MacCarthy, Finbar, Reynolds, John V., Kennedy, Breandán N., O’Sullivan, Jacintha
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7374542/
https://ncbi.nlm.nih.gov/pubmed/32694701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68777-7
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