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Chemotherapy regimens induce inhibitory immune checkpoint protein expression on stem-like and senescent-like oesophageal adenocarcinoma cells

Use of immune checkpoint inhibitors (ICIs) with chemotherapy to enhance responses in oesophageal adenocarcinoma (OAC) is an attractive approach. We identified subpopulations of OAC cells expressing inhibitory immune checkpoint (IC) ligands (PD-L1, PD-L2 and CD160) and receptors (PD-1, TIGIT, TIM-3,...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Davern, Maria, Donlon, Noel E., Sheppard, Andrew, Connell, Fiona O’, Hayes, Conall, Bhardwaj, Anshul, Foley, Emma, Toole, Dermot O’, Lynam-Lennon, Niamh, Ravi, Narayanasamy, Reynolds, John V., Maher, Stephen G., Lysaght, Joanne
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8008239/
https://ncbi.nlm.nih.gov/pubmed/33765543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2021.101062
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