Chemotherapy regimens induce inhibitory immune checkpoint protein expression on stem-like and senescent-like oesophageal adenocarcinoma cells

Use of immune checkpoint inhibitors (ICIs) with chemotherapy to enhance responses in oesophageal adenocarcinoma (OAC) is an attractive approach. We identified subpopulations of OAC cells expressing inhibitory immune checkpoint (IC) ligands (PD-L1, PD-L2 and CD160) and receptors (PD-1, TIGIT, TIM-3,...

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Dettagli Bibliografici
Pubblicato in:Transl Oncol
Autori principali: Davern, Maria, Donlon, Noel E., Sheppard, Andrew, Connell, Fiona O’, Hayes, Conall, Bhardwaj, Anshul, Foley, Emma, Toole, Dermot O’, Lynam-Lennon, Niamh, Ravi, Narayanasamy, Reynolds, John V., Maher, Stephen G., Lysaght, Joanne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press 2021
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8008239/
https://ncbi.nlm.nih.gov/pubmed/33765543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2021.101062
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