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Induction of heat shock protein 70 inhibits ischemic renal injury

Heat shock protein 70 (Hsp70) is a potent antiapoptotic agent. Here, we tested whether it directly regulates renal cell survival and organ function in a model of transient renal ischemia using Hsp70 knockout, heterozygous, and wild-type mice. The kidney cortical Hsp70 content inversely correlated wi...

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Publicat a:Kidney Int
Autors principals: Wang, Zhiyong, Gall, Jonathan M., Bonegio, Ramon G.B., Havasi, Andrea, Hunt, Clayton R., Sherman, Michael Y., Schwartz, John H., Borkan, Steven C.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006160/
https://ncbi.nlm.nih.gov/pubmed/21270764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2010.527
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