Inhibition of Heat Shock Induction of Heat Shock Protein 70 and Enhancement of Heat Shock Protein 27 Phosphorylation by Quercetin Derivatives

Inhibitors of heat-induced heat shock protein 70 (HSP70) expression have the potential to enhance the therapeutic effectiveness of heat induced radiosensitization of tumors. Among known small molecule inhibitors, quercetin has the advantage of being easily modified for structure-activity studies. He...

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Huvudupphovsmän: Wang, Rongsheng E., Kao, Jeffrey L.-F., Hilliard, Carolyn A., Pandita, Raj K., Roti, Joseph L. Roti, Hunt, Clayton R., Taylor, John-Stephen
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763579/
https://ncbi.nlm.nih.gov/pubmed/19296652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm801445c
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